Endocrine complications of topical and intralesional corticosteroid therapy.

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Endocrine complications of topical and intralesional corticosteroid therapy.

Four previously healthy children acquired skin problems that were treated with topical or intralesional fluorinated corticosteroids. Three developed signs that suggested Cushing's syndrome 1-4 months after initial treatment. Investigation showed low plasma cortisol levels and inadequate response to corticotrophin stimulation. After 7 months of treatment with topical steroids the fourth child pr...

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Proliferative and necrotising otitis externa (PNOE) is a very rare disease affecting the ear canals and concave pinnae of kittens. This report describes a 5-month-old cat with PNOE. Histopathological examination confirmed the diagnosis. Treatment was initiated with local injection of methylprednisolone acetate into the lesions. The cat was subsequently treated with clobetasol propionate cream, ...

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Intralesional corticosteroid therapy for infantile hemangiomas.

Intralesional corticosteroid injections were performed in 31 hemangiomas in 30 infants aged 1 to 10 months at first injection. One to five injections were given, spaced 6 weeks apart. Lesions were located throughout the head and neck region, except one that was on the buttock. A mixture of betamethasone acetate and triamcinolone acetonide was used. Four lesions (13 percent) virtually disappeare...

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Nonsurgical Management of Oral Mucocele by Intralesional Corticosteroid Therapy

Background. Oral mucocele is a common lesion resulting from an alteration of minor salivary glands due to mucus accumulation. Rapid appearance, specific location, history of trauma, bluish colour, and consistency help in the diagnosis. Conventional surgical removal is the treatment of choice but has several disadvantages like damage to adjacent ducts with further development of satellite lesion...

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Intralesional corticosteroid therapy in hemangiomas: clinical outcome in 160 cases.

BACKGROUND Hemangiomas, one of the most common childhood neoplasms, exhibit a characteristic history of rapid proliferation and slow spontaneous involution. Most of hemangiomas are often managed conversatively, requiring numerous years for spontaneous involution. However hemangiomas can threaten function in 10% to 20% of cases, less than 1% are truly life threatening. All these serious hemangio...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1982

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.57.3.204